Stasis Thrombi Induced by Bacterial Endotoxin

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Stasis Thrombi Induced by Bacterial Endotoxin.

• Previous studies in this laboratory have indicated that a combination of systemic hypercoagulability and retarded blood flow is capable of producing a red thrombus in the veins of animals. The hypothesis has been proposed that activation of the procoagulants involved in the formation of intrinsic thromboplastin produces massive thrombosis in large vessels in areas of markedly reduced blood fl...

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Alterations in the Blood Coagulation System Induced by Bacterial Endotoxin

The intravenous injection of bacterial endotoxins alter the coagulation system of rabbits' blood in vivo. Twenty-four hours after the first injection the fibrinogen level rises to twice normal values. The second injection at this time causes a 30 to 40 per cent decrease in fibrinogen content in 4 hours. Twenty hours later it again rises to twice normal values. A marked decrease in whole blood c...

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Bacterial Endocarditis and Mural Thrombi

EMBOLIC phenomena occur with such frequency in the course of bacterial endocarditis as to constitute a cardinal diagnostic feature of this disease. However, it has been noted that the resultant infarcts are less often septic than would be expected if the emboli originated from the infected valvular vegetations.' A previous study of this apparent paradox showed that it is the nonbacterial thromb...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1964

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.14.6.486